| Title: | Electrostatically immobilised BOX and PYBOX metal catalysts: application to ene reactions
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| Authors: | McDonagh C. and O'Leary P., 2009 |
| Abstract: | Copper(I), copper(II) and scandium(III) triflate complexes of BOX and PYBOX ligands have been electrostatically immobilised on silica. The performance of the immobilised catalysts, in the two carbonyl-ene reactions studied, compares very well with that of their homogeneous equivalents. The immobilised catalysts were successfully reused a number of times. In the case of a scandium complex, a variation in enantioselectivity of up to 73% was observed on immobilisation compared to its use homogeneously. The reason for this variation in enantioselectivity is explored with the aid of molecular modelling. |
| ICHEC Project: | Modeling of silica surface interactions with transition metal catalysts |
| Publication: | Tetrahedron Letters (2009) 50:979–982 |
| URL: | http://dx.doi.org/10.1016/j.tetlet.2008.12.046 |
| Keywords: | Copper; Scandium(III); Bis(oxazolinyl)pyridine; Bis(oxazoline); Electrostatic immobilisation; Ene reaction; Silica; Molecular modelling |
| Status: | Published |
