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ICHEC Software

Information about software packages installed on the ICHEC systems.


Versions Installed

Stokes: 8.93


T-Coffee is a multiple sequence alignment package. You can use T-Coffee to align sequences or to combine the output of your favorite alignment methods (Clustal, Mafft, Probcons, Muscle...) into one unique alignment (M-Coffee).

T-Coffee can align protein, DNA and RNA sequences. It is also able to combine sequence information with protein structural information (3D-Coffee/Expresso), profile information (PSI-Coffee) or RNA secondary structures (R-Coffee).


T-Coffee is a freeware opensource package distributed under the GNU public license.



Additional Notes

To use T-Coffee load the relevant environment module:

module load t-coffee

Further information can be obtained from http://www.tcoffee.org/Projects_home_page/t_coffee_home_page.html.

How to cite T-Coffee:

Notredame C., Higgins D.G. and Heringa J. (2000)
T-Coffee: A novel method for fast and accurate multiple sequence alignment.
Journal of Molecular Biology 302(1): 205-217.

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